Lung and Gut Microbiota Changes Associated with <i>Pseudomonas aeruginosa</i> Infection in Mouse Models of Cystic Fibrosis.

Bacci, Giovanni; Rossi, Alice; Armanini, Federica; Cangioli, Lisa; De Fino, Ida; Segata, Nicola; Mengoni, Alessio; Bragonzi, Alessandra; Bevivino, Annamaria

Lung and Gut Microbiota Changes Associated with Pseudomonas aeruginosa Infection in Mouse Models of Cystic Fibrosis.

Bacci, Giovanni; Rossi, Alice; Armanini, Federica; Cangioli, Lisa; De Fino, Ida; Segata, Nicola; Mengoni, Alessio; Bragonzi, Alessandra; Bevivino, Annamaria.

Afiliação

Bacci G; Department of Biology, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
Rossi A; Infections and Cystic Fibrosis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Armanini F; Department CIBIO, University of Trento, 38122 Trento, Italy.
Cangioli L; Department of Biology, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
De Fino I; Infections and Cystic Fibrosis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Segata N; Department CIBIO, University of Trento, 38122 Trento, Italy.
Mengoni A; Department of Biology, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
Bragonzi A; Infections and Cystic Fibrosis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Bevivino A; Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, ENEA Casaccia Research Center, 00123 Rome, Italy.

Int J Mol Sci ; 22(22)2021 Nov 10.

Article em En | MEDLINE | ID: mdl-34830048

Assuntos

Fibrose Cística/metabolismo; Fibrose Cística/microbiologia; Trato Gastrointestinal/metabolismo; Trato Gastrointestinal/microbiologia; Pulmão/metabolismo; Pulmão/microbiologia; Infecções por Pseudomonas/metabolismo; Animais; Peso Corporal; Regulador de Condutância Transmembrana em Fibrose Cística/genética; Modelos Animais de Doenças; Disbiose/genética; Disbiose/microbiologia; Fezes/microbiologia; Camundongos; Microbiota/genética; Infecção Persistente/metabolismo; Infecção Persistente/microbiologia; Análise de Componente Principal; Infecções por Pseudomonas/microbiologia; RNA Ribossômico 16S/genética

Palavras-chave

CFTR mice; Pseudomonas aeruginosa; animal models; cystic fibrosis; gut; gut-lung axis; lung; microbiome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Pseudomonas / Fibrose Cística / Trato Gastrointestinal / Pulmão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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