LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway.

Xing, Ying; Liu, Yang; Qi, Zhong; Liu, Zhengrong; Wang, Xin; Zhang, Hongyi

Xing, Ying; Liu, Yang; Qi, Zhong; Liu, Zhengrong; Wang, Xin; Zhang, Hongyi.

Afiliação

Xing Y; Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4th Ring West Road, Fengtai District, Beijing, 100070, China.
Liu Y; Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4th Ring West Road, Fengtai District, Beijing, 100070, China.
Qi Z; Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4th Ring West Road, Fengtai District, Beijing, 100070, China.
Liu Z; Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4th Ring West Road, Fengtai District, Beijing, 100070, China.
Wang X; Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4th Ring West Road, Fengtai District, Beijing, 100070, China.
Zhang H; Department of General Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119, South 4th Ring West Road, Fengtai District, Beijing, 100070, China. zhhycsy@163.com.

Cell Mol Biol Lett ; 26(1): 49, 2021 Nov 27.

Article em En | MEDLINE | ID: mdl-34837962

Assuntos

Apoptose/genética; Carcinoma Hepatocelular/genética; Proteínas de Transporte/genética; Movimento Celular/genética; Proliferação de Células/genética; MAP Quinases Reguladas por Sinal Extracelular/genética; Proteínas Quinases JNK Ativadas por Mitógeno/genética; Neoplasias Hepáticas/genética; Animais; Linhagem Celular Tumoral; Feminino; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Sistema de Sinalização das MAP Quinases/genética; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Transdução de Sinais/genética

Palavras-chave

Hepatocellular carcinoma; JNK and ERK signaling pathway; L antigen family member 3; Malignant phenotypes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Movimento Celular / Apoptose / Carcinoma Hepatocelular / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Quinases JNK Ativadas por Mitógeno / Proliferação de Células / Neoplasias Hepáticas Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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