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A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC.
Lu, Yue; Fan, Zhenzhen; Zhu, Su-Jie; Huang, Xiaoxing; Zhuang, Zhongji; Li, Yunzhan; Deng, Zhou; Gao, Lei; Hong, Xuehui; Zhang, Ting; Li, Li; Sun, Xihuan; Huang, Wei; Zhang, Jingfang; Liu, Yan; Zhang, Baoding; Jiang, Jie; Gui, Fu; Wang, Zheng; Li, Qiyuan; Song, Siyang; Huang, Xin; Wu, Qiao; Chen, Lanfen; Zhou, Dawang; Zhang, Jianming; Yun, Cai-Hong; Chen, Liang; Deng, Xianming.
Afiliação
  • Lu Y; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Fan Z; Institute of Life and Health Engineering, Jinan University, Guangzhou, China.
  • Zhu SJ; Department of Biochemistry and Biophysics, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China.
  • Huang X; Beijing Key Laboratory of Tumor Systems Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Zhuang Z; Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, China.
  • Li Y; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Deng Z; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Gao L; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Hong X; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Zhang T; Institute of Life and Health Engineering, Jinan University, Guangzhou, China.
  • Li L; Department of Gastrointestinal Surgery, Affiliated Zhongshan Hospital of Xiamen University, Xiamen, China.
  • Sun X; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Huang W; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Zhang J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Liu Y; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Zhang B; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Jiang J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Gui F; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Wang Z; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Li Q; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Song S; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Huang X; National Institute for Data Science in Health and Medicine, School of Medicine, Xiamen University, Xiamen, China.
  • Wu Q; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Chen L; Division of Drug Discovery, Hongyun Biotech Co., Ltd., Nanjing, China.
  • Zhou D; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Zhang J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Yun CH; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Chen L; National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Deng X; Department of Biochemistry and Biophysics, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China.
EMBO Mol Med ; 14(1): e14296, 2022 01 11.
Article em En | MEDLINE | ID: mdl-34845836

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Quinase do Linfoma Anaplásico / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Quinase do Linfoma Anaplásico / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article