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Allosteric ligands control the activation of a class C GPCR heterodimer by acting at the transmembrane interface.
Liu, Lei; Fan, Zhiran; Rovira, Xavier; Xue, Li; Roux, Salomé; Brabet, Isabelle; Xin, Mingxia; Pin, Jean-Philippe; Rondard, Philippe; Liu, Jianfeng.
Afiliação
  • Liu L; Cellular Signaling Laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, and College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
  • Fan Z; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
  • Rovira X; Cellular Signaling Laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, and College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
  • Xue L; MCS, Laboratory of Medicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain.
  • Roux S; Cellular Signaling Laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, and College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
  • Brabet I; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
  • Xin M; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
  • Pin JP; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
  • Rondard P; Cellular Signaling Laboratory, International Research Center for Sensory Biology and Technology of MOST, Key Laboratory of Molecular Biophysics of MOE, and College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
  • Liu J; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Elife ; 102021 12 06.
Article em En | MEDLINE | ID: mdl-34866572

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de GABA-B Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de GABA-B Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article