Computational tools for assessing gene therapy under branching process models of mutation.

Stutz, Timothy C; Sinsheimer, Janet S; Sehl, Mary; Xu, Jason

Stutz, Timothy C; Sinsheimer, Janet S; Sehl, Mary; Xu, Jason.

Afiliação

Stutz TC; Department of Computational Medicine, University of California, Los Angeles, CA, USA.
Sinsheimer JS; Departments of Biostatistics, Computational Medicine, Human Genetics, University of California, Los Angeles, CA, USA.
Sehl M; Department of Computational Medicine and Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Xu J; Department of Statistical Science, Duke University, Durham, NC, USA. jason.q.xu@duke.edu.

Bull Math Biol ; 84(1): 15, 2021 12 06.

Article em En | MEDLINE | ID: mdl-34870755

Assuntos

Transplante de Células-Tronco Hematopoéticas; Modelos Biológicos; Terapia Genética; Conceitos Matemáticos; Mutação; Processos Estocásticos; Transplante Autólogo

Palavras-chave

Conditional moments; Generating functions; Hematopoiesis; Mechanistic models; Mutagenesis; Stochastic population processes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Células-Tronco Hematopoéticas / Modelos Biológicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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