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Outcomes of atrial fibrillation in patients with COVID-19 pneumonia: A systematic review and meta-analysis.
Chen, Ming-Yue; Xiao, Fang-Ping; Kuai, Lin; Zhou, Hai-Bo; Jia, Zhi-Qiang; Liu, Meng; He, Hao; Hong, Mei.
Afiliação
  • Chen MY; Department of Geriatrics, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Xiao FP; Department of Cardiology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Kuai L; Department of Geriatrics, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Zhou HB; Department of Cardiology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Jia ZQ; Department of Cardiology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Liu M; Department of Cardiology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • He H; Department of Cardiology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Hong M; Department of Geriatrics, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China; Department of Cardiology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: meihong@njmu.edu.cn.
Am J Emerg Med ; 50: 661-669, 2021 Dec.
Article em En | MEDLINE | ID: mdl-34879483
BACKGROUND: Recently, emerging evidence has suggested that atrial fibrillation (AF) has an epidemiological correlation with coronavirus disease 2019 (COVID-19). However, the clinical outcomes of AF in COVID-19 remain inconsistent and inconclusive. The aim of this study was to provide a comprehensive description of the impact of AF on the prognosis of patients with COVID-19 pneumonia. METHODS: Three electronic databases (PubMed, Embase, and Web of Science) were searched for eligible studies as of March 1, 2021. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were used to evaluate the associations between AF (preexisting and new-onset) and in-hospital mortality, post-discharge mortality, and ventilator use. RESULTS: A total of 36 individual studies were incorporated into our meta-analysis. The combined results revealed that preexisting AF was associated with increased in-hospital mortality (pooled OR: 2.07; 95% CI: 1.60-2.67; p < 0.001), post-discharge mortality (pooled OR: 2.69; 95% CI: 1.24-5.83; p < 0.05), and ventilator utilization (pooled OR: 4.53; 95% CI: 1.33-15.38; p < 0.05) in patients with COVID-19. In addition, our data demonstrated that new-onset AF during severe acute respiratory syndrome coronavirus 2 infection was significantly correlated with increased mortality (pooled OR: 2.38; 95% CI: 2.04-2.77; p < 0.001). CONCLUSIONS: The presence of AF is correlated with adverse outcomes in patients with COVID-19 pneumonia, which deserves increased attention and should be managed appropriately to prevent adverse outcomes.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / COVID-19 Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / COVID-19 Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article