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Janus kinase inhibition in induction treatment of anti-MDA5 juvenile dermatomyositis-associated rapidly progressive interstitial lung disease.
Chan Ng, Poh Lin Pauline; Mopur, Archana; Goh, Daniel Yam Thiam; Ramamurthy, Mahesh Babu; Lim, Michael Teik Chung; Lim, Lee Kean; Ooi, Pei Ling; Ang, Elizabeth Youning.
Afiliação
  • Chan Ng PLP; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
  • Mopur A; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Goh DYT; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
  • Ramamurthy MB; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
  • Lim MTC; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Lim LK; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
  • Ooi PL; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Ang EY; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Int J Rheum Dis ; 25(2): 228-231, 2022 Feb.
Article em En | MEDLINE | ID: mdl-34882988
ABSTRACT
Tofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin-18 are useful markers for tracking activity and response of JDM-associated ILD.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Pirimidinas / Doenças Pulmonares Intersticiais / Dermatomiosite / Inibidores de Janus Quinases Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Child / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Pirimidinas / Doenças Pulmonares Intersticiais / Dermatomiosite / Inibidores de Janus Quinases Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Child / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article