Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium <i>Lentzea</i> sp. GA3-008.

Liu, Hong-Bing; Davison, Jack R; Rajwani, Rahim; Zhao, Gengxiang; Ohlemacher, Shannon I; O'Connor, Robert D; Bewley, Carole A

Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium Lentzea sp. GA3-008.

Liu, Hong-Bing; Davison, Jack R; Rajwani, Rahim; Zhao, Gengxiang; Ohlemacher, Shannon I; O'Connor, Robert D; Bewley, Carole A.

Afiliação

Liu HB; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.
Davison JR; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.
Rajwani R; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.
Zhao G; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.
Ohlemacher SI; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.
O'Connor RD; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.
Bewley CA; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0820, USA.

Molecules ; 26(23)2021 Nov 27.

Article em En | MEDLINE | ID: mdl-34885778

Assuntos

Actinomycetales/química; Pirazinas/isolamento & purificação; Microbiologia do Solo; Vias Biossintéticas/genética; Espectroscopia de Ressonância Magnética Nuclear de Carbono-13; Genoma Bacteriano; Família Multigênica; Peptídeo Sintases/metabolismo; Espectroscopia de Prótons por Ressonância Magnética; Especificidade por Substrato

Palavras-chave

NRPS; actinomycetes; biosynthesis; cyclic dipeptides; genomics; heterocycles; natural products; structure elucidation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazinas / Microbiologia do Solo / Actinomycetales Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazinas / Microbiologia do Solo / Actinomycetales Idioma: En Ano de publicação: 2021 Tipo de documento: Article