Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice.

Casu, Carla; Liu, Alison; De Rosa, Gianluca; Low, Audrey; Suzuki, Aae; Sinha, Sayantani; Ginzburg, Yelena Z; Abrams, Charles; Aghajan, Mariam; Guo, Shuling; Rivella, Stefano

Casu, Carla; Liu, Alison; De Rosa, Gianluca; Low, Audrey; Suzuki, Aae; Sinha, Sayantani; Ginzburg, Yelena Z; Abrams, Charles; Aghajan, Mariam; Guo, Shuling; Rivella, Stefano.

Afiliação

Casu C; Division of Hematology, Department of Pediatrics, The Children's Hospital of Philadelphia (CHOP), Philadelphia, PA, United States of America.
Liu A; Division of Hematology, Department of Pediatrics, The Children's Hospital of Philadelphia (CHOP), Philadelphia, PA, United States of America.
De Rosa G; Division of Hematology, Department of Pediatrics, The Children's Hospital of Philadelphia (CHOP), Philadelphia, PA, United States of America.
Low A; Ionis Pharmaceuticals, Inc., Carlsbad, CA, United States of America.
Suzuki A; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, United States of America.
Sinha S; Division of Hematology, Department of Pediatrics, The Children's Hospital of Philadelphia (CHOP), Philadelphia, PA, United States of America.
Ginzburg YZ; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Abrams C; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, United States of America.
Aghajan M; Ionis Pharmaceuticals, Inc., Carlsbad, CA, United States of America.
Guo S; Ionis Pharmaceuticals, Inc., Carlsbad, CA, United States of America.
Rivella S; Division of Hematology, Department of Pediatrics, The Children's Hospital of Philadelphia (CHOP), Philadelphia, PA, United States of America.

PLoS One ; 16(12): e0251995, 2021.

Article em En | MEDLINE | ID: mdl-34890402

Assuntos

Proteínas de Membrana/antagonistas & inibidores; Oligonucleotídeos Antissenso/farmacologia; Policitemia Vera/tratamento farmacológico; Animais; Humanos; Janus Quinase 2/genética; Janus Quinase 2/metabolismo; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Camundongos Transgênicos; Oligonucleotídeos Antissenso/genética; Policitemia Vera/genética; Policitemia Vera/metabolismo; RNA Mensageiro/antagonistas & inibidores; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Serina Endopeptidases/genética; Serina Endopeptidases/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Policitemia Vera / Oligonucleotídeos Antissenso / Proteínas de Membrana Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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