Dietary glycemic load and its association with glucose metabolism and lipid profile in young adults.
Nutr Metab Cardiovasc Dis
; 32(1): 125-133, 2022 01.
Article
em En
| MEDLINE
| ID: mdl-34893403
ABSTRACT
BACKGROUND AND AIM:
To evaluate the association of Glycemic Load (GL) with glucose metabolism and blood lipids among young adults. METHODS ANDRESULTS:
This study included 1538 participants (51% females), evaluated at 21 years of age as part of the EPITeen cohort. The GL of each individual was obtained from the assessment of their dietary intake by using a 86-item semi-quantitative food frequency questionnaire. The evaluation included anthropometric measurements and a fasting blood sample was used to measure glucose, insulin, triglycerides, total cholesterol, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Insulin resistance was calculated based on the homeostasis model method (HOMA-IR). The association between the GL and the biochemical parameters was evaluated by linear regression models using ß and 95% confidence intervals (95% CI), stratified by sex and adjusted for body mass index (BMI), energy and fiber intake, and self-perceived social class. No association was found between GL and the glucose metabolism parameters after adjustment. Regarding blood lipids, a positive association was found with LDL-C (ß = 1.507, 95% CI 0.454; 2.561 for females; ß = 0.216, 95% CI -0.587; 1.020 for males) and a negative association with HDL-C (ß = -0.647, 95% CI -1.112; -0.181 for females; ß = -0.131, 95% CI -0.422; 0.160 for males).CONCLUSIONS:
Our results suggest that, in healthy young subjects, a high GL diet may have a negative impact on lipid profile.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Carga Glicêmica
Tipo de estudo:
Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article