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Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction.
Diorio, Caroline; Shraim, Rawan; Vella, Laura A; Giles, Josephine R; Baxter, Amy E; Oldridge, Derek A; Canna, Scott W; Henrickson, Sarah E; McNerney, Kevin O; Balamuth, Frances; Burudpakdee, Chakkapong; Lee, Jessica; Leng, Tomas; Farrel, Alvin; Lambert, Michele P; Sullivan, Kathleen E; Wherry, E John; Teachey, David T; Bassiri, Hamid; Behrens, Edward M.
Afiliação
  • Diorio C; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Shraim R; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Vella LA; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Giles JR; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Baxter AE; Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Oldridge DA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Canna SW; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Henrickson SE; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.
  • McNerney KO; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Balamuth F; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.
  • Burudpakdee C; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Lee J; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.
  • Leng T; Division of Pathology and Laboratory Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Farrel A; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Lambert MP; Division of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Sullivan KE; Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Wherry EJ; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Teachey DT; Division of Emergency Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Bassiri H; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Behrens EM; Immune Dysregulation Frontier Program, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Nat Commun ; 12(1): 7222, 2021 12 10.
Article em En | MEDLINE | ID: mdl-34893640
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Interferon gama / Síndrome de Resposta Inflamatória Sistêmica / Proteoma / COVID-19 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Interferon gama / Síndrome de Resposta Inflamatória Sistêmica / Proteoma / COVID-19 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article