Structure driven compound optimization in targeted protein degradation.

Leissing, Thomas M; Luh, Laura M; Cromm, Philipp M

Leissing, Thomas M; Luh, Laura M; Cromm, Philipp M.

Afiliação

Leissing TM; Evotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Luh LM; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany.
Cromm PM; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany. Electronic address: philipp.cromm@bayer.com.

Drug Discov Today Technol ; 37: 73-82, 2020 Dec.

Article em En | MEDLINE | ID: mdl-34895657

Assuntos

Complexo de Endopeptidases do Proteassoma; Ubiquitina-Proteína Ligases; Complexo de Endopeptidases do Proteassoma/metabolismo; Proteólise; Ubiquitina; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitinação

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Complexo de Endopeptidases do Proteassoma Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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