Perinatal and birth correlates of childhood irritability in Taiwan's national epidemiological study.
J Affect Disord
; 299: 273-280, 2022 02 15.
Article
em En
| MEDLINE
| ID: mdl-34906640
ABSTRACT
BACKGROUND:
Childhood irritability, characterized by low frustration tolerance and developmentally-inappropriate temper outbursts, is a transdiagnostic symptom in child psychiatry. Little is known regarding the influences of early experience and environmental exposure on irritability from a perinatal perspective. This study examined the associations between irritability and multiple perinatal and birth factors.METHODS:
Drawn Taiwan's National Epidemiological Study of Child Mental Disorders, 5124 children (2591 females) aged 7.7 to 14.6 years (mean 11.2 years) and their parents completed the Affective Reactivity Index, a well-established irritability measure. Parents completed a survey on parental, perinatal, and birth characteristics. Multiple linear regression models were performed to examine the associations between perinatal and birth characteristics and child irritability reported across informants.RESULTS:
Maternal smoking, vaginal bleeding, and pre-eclampsia during pregnancy and phototherapy for jaundice >3 days were associated with high irritability after adjusting for child's age, sex, and parental characteristics. Findings were consistent across parent- and child-rated irritability.LIMITATIONS:
Retrospective assessment of early exposures may be subject to recall bias despite previously-established validity and reliability. Longitudinal research with prospective assessments of early life exposures is recommended to confirm our findings. This exploratory approach of multiple survey items also precludes more in-depth assessments of perinatal risks for developing irritability.CONCLUSIONS:
This study provides novel evidence suggesting a perinatal link with irritability in a national sample of youths. Given that irritability predicts adverse mental health and life outcomes, identifying its perinatal and birth predictors may inform early etiology, guiding timely assessment and intervention.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Humor Irritável
/
Transtornos do Humor
Tipo de estudo:
Observational_studies
/
Prognostic_studies
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Qualitative_research
/
Risk_factors_studies
Limite:
Adolescent
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Female
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Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article