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Selective retinal ganglion cell loss and optic neuropathy in a humanized mouse model of familial dysautonomia.
Chekuri, Anil; Logan, Emily M; Krauson, Aram J; Salani, Monica; Ackerman, Sophie; Kirchner, Emily G; Bolduc, Jessica M; Wang, Xia; Dietrich, Paula; Dragatsis, Ioannis; Vandenberghe, Luk H; Slaugenhaupt, Susan A; Morini, Elisabetta.
Afiliação
  • Chekuri A; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Logan EM; Department of Neurology, Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA, USA.
  • Krauson AJ; Grousbeck Gene Therapy Center, Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
  • Salani M; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Ackerman S; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Kirchner EG; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Bolduc JM; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Wang X; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Dietrich P; Center for Genomic Medicine, Massachusetts General Hospital Research Institute, Boston, MA, USA.
  • Dragatsis I; Grousbeck Gene Therapy Center, Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
  • Vandenberghe LH; Department of Physiology, The University of Tennessee, Health Science Center, Memphis, TN, USA.
  • Slaugenhaupt SA; Department of Physiology, The University of Tennessee, Health Science Center, Memphis, TN, USA.
  • Morini E; Grousbeck Gene Therapy Center, Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Hum Mol Genet ; 31(11): 1776-1787, 2022 06 04.
Article em En | MEDLINE | ID: mdl-34908112
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Ganglionares da Retina / Disautonomia Familiar / Doenças do Nervo Óptico / Doenças Neurodegenerativas / Peptídeos e Proteínas de Sinalização Intracelular Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Ganglionares da Retina / Disautonomia Familiar / Doenças do Nervo Óptico / Doenças Neurodegenerativas / Peptídeos e Proteínas de Sinalização Intracelular Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article