Protective and pathological roles of regulatory immune cells in human cytomegalovirus infection following hematopoietic stem cell transplantation.
Rev Med Virol
; 32(4): e2319, 2022 07.
Article
em En
| MEDLINE
| ID: mdl-34914147
ABSTRACT
Human cytomegalovirus (HCMV) is ubiquitously prevalent. Immune system in healthy individuals is capable of controlling HCMV infection; however, HCMV can be life-threatening for immunocompromised individuals, such as transplant recipients. Both innate and adaptive immune systems are critically involved in the HCMV infection. Recent studies have indicated that regulatory immune cells which play essential roles in maintaining a healthy immune environment are closely related to immune response in HCMV infection. However, the exact role of regulatory immune cells in immune regulation and homoeostasis during the battle between HCMV and host still requires further research. In this review, we highlight the protective and pathological roles of regulatory immune cells in HCMV infection following hematopoietic stem cell transplantation (HSCT).
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Infecções por Citomegalovirus
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Infecções por Herpesviridae
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Transplante de Células-Tronco Hematopoéticas
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article