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Epac1-/- and Epac2-/- mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation.
Tomilin, Viktor N; Pyrshev, Kyrylo; Stavniichuk, Anna; Hassanzadeh Khayyat, Naghmeh; Ren, Guohui; Zaika, Oleg; Khedr, Sherif; Staruschenko, Alexander; Mei, Fang C; Cheng, Xiaodong; Pochynyuk, Oleh.
Afiliação
  • Tomilin VN; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Pyrshev K; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Stavniichuk A; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Hassanzadeh Khayyat N; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Ren G; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Zaika O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Khedr S; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Staruschenko A; Department of Physiology, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.
  • Mei FC; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Cheng X; Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, USA.
  • Pochynyuk O; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
JCI Insight ; 7(3)2022 02 08.
Article em En | MEDLINE | ID: mdl-34914636

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sódio / Canais de Cálcio / Regulação da Expressão Gênica / Fatores de Troca do Nucleotídeo Guanina / Canais de Cátion TRPV / Nefropatias / Natriurese Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sódio / Canais de Cálcio / Regulação da Expressão Gênica / Fatores de Troca do Nucleotídeo Guanina / Canais de Cátion TRPV / Nefropatias / Natriurese Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article