Your browser doesn't support javascript.
loading
A retrospective analysis of fibrinolytic and adjunctive antithrombotic treatment during cardiopulmonary resuscitation.
Weiss, Armin; Frisch, Christoph; Hornung, Rouven; Baubin, Michael; Lederer, Wolfgang.
Afiliação
  • Weiss A; Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
  • Frisch C; Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria. Christoph.frisch@i-med.ac.at.
  • Hornung R; Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
  • Baubin M; Department of Anesthesiology and Critical Care Medicine, University Hospital of Innsbruck, 6020, Innsbruck, Austria.
  • Lederer W; Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Sci Rep ; 11(1): 24095, 2021 12 16.
Article em En | MEDLINE | ID: mdl-34916555
Synergistic effects of fibrinolytic and additional antithrombotic treatment during cardiopulmonary resuscitation in out-of-hospital cardiac arrest of assumed cardiac origin were evaluated retrospectively. Data were drawn from electronic files of the physician-staffed Emergency Medical Services Tyrol. During a 22-month observation period 53 adult patients were treated with tenecteplase (mean 7641 IU), 19 (32.1%) of whom received additional antithrombotic treatment with heparin (4000-5000 IU) and acetylsalicylic acid (250-500 mg). Lasting return of spontaneous circulation occurred in four of 34 patients who received fibrinolytic treatment only and in seven of 19 patients with additional antithrombotic treatment (p = 0.037). Four of five patients who were discharged from hospital had received additional antithrombotic treatment during CPR and were in appropriate neurological status (CPC 1). Considering the small sample size in this retrospective study, the argument may be still be made that fibrinolytic and adjunctive antithrombotic treatment during cardiopulmonary resuscitation in out-of-hospital cardiac arrest of assumed cardiac origin may increase the chances for survival.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Heparina / Aspirina / Reanimação Cardiopulmonar / Parada Cardíaca Extra-Hospitalar / Fibrinolíticos / Tenecteplase Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Heparina / Aspirina / Reanimação Cardiopulmonar / Parada Cardíaca Extra-Hospitalar / Fibrinolíticos / Tenecteplase Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article