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Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor.
Capraz, Tümay; Kienzl, Nikolaus F; Laurent, Elisabeth; Perthold, Jan W; Föderl-Höbenreich, Esther; Grünwald-Gruber, Clemens; Maresch, Daniel; Monteil, Vanessa; Niederhöfer, Janine; Wirnsberger, Gerald; Mirazimi, Ali; Zatloukal, Kurt; Mach, Lukas; Penninger, Josef M; Oostenbrink, Chris; Stadlmann, Johannes.
Afiliação
  • Capraz T; Institute for Molecular Modeling and Simulation, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Kienzl NF; Institute of Plant Biotechnology and Cell Biology, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Laurent E; Institute of Molecular Biotechnology, Department of Biotechnology and Core Facility Biomolecular & Cellular Analysis, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Perthold JW; Institute for Molecular Modeling and Simulation, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Föderl-Höbenreich E; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
  • Grünwald-Gruber C; Institute of Biochemistry, Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Maresch D; Institute of Biochemistry, Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Monteil V; Karolinska Institute, Department of Laboratory Medicine, Stockholm, Sweden.
  • Niederhöfer J; Apeiron Biologics, Vienna, Austria.
  • Wirnsberger G; Apeiron Biologics, Vienna, Austria.
  • Mirazimi A; Karolinska Institute, Department of Laboratory Medicine, Stockholm, Sweden.
  • Zatloukal K; National Veterinary Institute, Uppsala, Sweden.
  • Mach L; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
  • Penninger JM; Institute of Plant Biotechnology and Cell Biology, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria.
  • Oostenbrink C; IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr, Vienna, Austria.
  • Stadlmann J; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, Canada.
Elife ; 102021 12 20.
Article em En | MEDLINE | ID: mdl-34927585
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polissacarídeos / Receptores Virais / Simulação de Dinâmica Molecular / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polissacarídeos / Receptores Virais / Simulação de Dinâmica Molecular / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article