Your browser doesn't support javascript.
loading
Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021.
Lewis, Nathaniel M; Naioti, Eric A; Self, Wesley H; Ginde, Adit A; Douin, David J; Keipp Talbot, H; Casey, Jonathan D; Mohr, Nicholas M; Zepeski, Anne; Gaglani, Manjusha; Ghamande, Shekhar A; McNeal, Tresa A; Shapiro, Nathan I; Gibbs, Kevin W; Clark Files, D; Hager, David N; Shehu, Arber; Prekker, Matthew E; Erickson, Heidi L; Gong, Michelle N; Mohamed, Amira; Henning, Daniel J; Steingrub, Jay S; Peltan, Ithan D; Brown, Samuel M; Martin, Emily T; Hubel, Kinsley; Hough, Catherine L; Busse, Laurence W; Ten Lohuis, Caitlin C; Duggal, Abhijit; Wilson, Jennifer G; Gordon, Alexandra J; Qadir, Nida; Chang, Steven Y; Mallow, Christopher; Rivas, Carolina; Babcock, Hilary M; Kwon, Jennie H; Exline, Matthew C; Halasa, Natasha; Chappell, James D; Lauring, Adam S; Grijalva, Carlos G; Rice, Todd W; Rhoads, Jillian P; Stubblefield, William B; Baughman, Adrienne; Womack, Kelsey N; Lindsell, Christopher J.
Afiliação
  • Lewis NM; Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia, USA.
  • Naioti EA; Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia, USA.
  • Self WH; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Ginde AA; University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Douin DJ; University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Keipp Talbot H; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Casey JD; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Mohr NM; University of Iowa, Iowa City, Iowa, USA.
  • Zepeski A; University of Iowa, Iowa City, Iowa, USA.
  • Gaglani M; Baylor Scott and White Health, Temple, Texas, USA.
  • Ghamande SA; Texas A&M University College of Medicine, Temple, Texas, USA.
  • McNeal TA; Baylor Scott and White Health, Temple, Texas, USA.
  • Shapiro NI; Baylor Scott and White Health, Temple, Texas, USA.
  • Gibbs KW; Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
  • Clark Files D; Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, USA.
  • Hager DN; Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, USA.
  • Shehu A; Johns Hopkins Hospital, Baltimore, Maryland, USA.
  • Prekker ME; Johns Hopkins Hospital, Baltimore, Maryland, USA.
  • Erickson HL; Hennepin County Medical Center, Minneapolis, Minnesota, USA.
  • Gong MN; Hennepin County Medical Center, Minneapolis, Minnesota, USA.
  • Mohamed A; Montefiore Healthcare Center, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Henning DJ; Montefiore Healthcare Center, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Steingrub JS; University of Washington School of Medicine, Seattle, Washington, USA.
  • Peltan ID; Baystate Medical Center, Springfield, Massachusetts, USA.
  • Brown SM; Intermountain Medical Center and University of Utah, Salt Lake City, Utah, USA.
  • Martin ET; Intermountain Medical Center and University of Utah, Salt Lake City, Utah, USA.
  • Hubel K; University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
  • Hough CL; Oregon Health and Science University Hospital, Portland, Oregon, USA.
  • Busse LW; Oregon Health and Science University Hospital, Portland, Oregon, USA.
  • Ten Lohuis CC; Emory University School of Medicine, Atlanta, Georgia, USA.
  • Duggal A; Emory University School of Medicine, Atlanta, Georgia, USA.
  • Wilson JG; Cleveland Clinic, Cleveland, Ohio, USA.
  • Gordon AJ; Stanford University School of Medicine, Palo Alto, California, USA.
  • Qadir N; Stanford University School of Medicine, Palo Alto, California, USA.
  • Chang SY; David Geffen School of Medicine at University of California Los Angeles, Ronald Reagan-University of California Los Angeles Medical Center, Los Angeles, California, USA.
  • Mallow C; David Geffen School of Medicine at University of California Los Angeles, Ronald Reagan-University of California Los Angeles Medical Center, Los Angeles, California, USA.
  • Rivas C; University of Miami, Miami, Florida, USA.
  • Babcock HM; University of Miami, Miami, Florida, USA.
  • Kwon JH; Washington University, St Louis, Missouri, USA.
  • Exline MC; Washington University, St Louis, Missouri, USA.
  • Halasa N; Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Chappell JD; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Lauring AS; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Grijalva CG; University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
  • Rice TW; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Rhoads JP; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Stubblefield WB; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Baughman A; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Womack KN; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Lindsell CJ; Vanderbilt University Medical Center, Nashville, Tennessee, USA.
J Infect Dis ; 225(10): 1694-1700, 2022 05 16.
Article em En | MEDLINE | ID: mdl-34932114
ABSTRACT
Vaccine effectiveness (VE) against COVID-19 hospitalization was evaluated among immunocompetent adults (≥18 years) during March-August 2021 using a case-control design. Among 1669 hospitalized COVID-19 cases (11% fully vaccinated) and 1950 RT-PCR-negative controls (54% fully vaccinated), VE was 96% (95% confidence interval [CI], 93%-98%) among patients with no chronic medical conditions and 83% (95% CI, 76%-88%) among patients with ≥ 3 categories of conditions. VE was similar between those aged 18-64 years versus ≥65 years (P > .05). VE against severe COVID-19 was very high among adults without chronic conditions and lessened with increasing comorbidity burden.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article