Exploring the Pharmacokinetics of Phenoxymethylpenicillin (Penicillin-V) in Adults: A Healthy Volunteer Study.
Open Forum Infect Dis
; 8(12): ofab573, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34934774
ABSTRACT
This healthy volunteer study aimed to explore phenoxymethylpenicillin (penicillin-V) pharmacokinetics (PK) to support the planning of large dosing studies in adults. Volunteers were dosed with penicillin-V at steady state. Total and unbound penicillin-V serum concentrations were determined, and a base population PK model was fitted to the data.
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MEDLINE
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En
Ano de publicação:
2021
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Article