Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice.

Segelcke, Daniel; Fischer, Hanna K; Hütte, Meike; Dennerlein, Sven; Benseler, Fritz; Brose, Nils; Pogatzki-Zahn, Esther M; Schmidt, Manuela

Segelcke, Daniel; Fischer, Hanna K; Hütte, Meike; Dennerlein, Sven; Benseler, Fritz; Brose, Nils; Pogatzki-Zahn, Esther M; Schmidt, Manuela.

Afiliação

Segelcke D; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany.
Fischer HK; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.
Hütte M; Somatosensory Signaling and Systems Biology, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Dennerlein S; Department of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany.
Benseler F; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Brose N; Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Pogatzki-Zahn EM; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany.
Schmidt M; Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria. Electronic address: manuela_schmidt@univie.ac.at.

Cell Rep ; 37(12): 110152, 2021 12 21.

Article em En | MEDLINE | ID: mdl-34936870

Assuntos

Citocinas/metabolismo; Proteínas de Membrana/imunologia; Proteínas de Membrana/metabolismo; Neuralgia/imunologia; Neuralgia/metabolismo; Traumatismos dos Nervos Periféricos/metabolismo; Células Receptoras Sensoriais/metabolismo; Animais; Comportamento Animal; Dor Crônica/imunologia; Dor Crônica/metabolismo; Feminino; Gânglios Espinais/metabolismo; Células HEK293; Humanos; Inflamação; Masculino; Proteínas de Membrana/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Neuroimunomodulação; Testes Neuropsicológicos; Transdução de Sinais; Canal de Cátion TRPA1/metabolismo

Palavras-chave

chronic pain; cytokines; dorsal root ganglia; incision pain; inflammatory signaling; mouse pain behavior; nerve injury; neuro-immune interaction; neuropathic pain; pain initiation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Receptoras Sensoriais / Citocinas / Traumatismos dos Nervos Periféricos / Proteínas de Membrana / Neuralgia Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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