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Production of 9,21-dihydroxy-20-methyl-pregna-4-en-3-one from phytosterols in Mycobacterium neoaurum by modifying multiple genes and improving the intracellular environment.
Yuan, Chen-Yang; Ma, Zhi-Guo; Zhang, Jing-Xian; Liu, Xiang-Cen; Du, Gui-Lin; Sun, Jun-Song; Shi, Ji-Ping; Zhang, Bao-Guo.
Afiliação
  • Yuan CY; Lab of Biorefinery, Shanghai Advanced Research Institute, Chinese Academy of Sciences, No. 99 Haike Road, Pudong, Shanghai, 201210, China.
  • Ma ZG; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Zhang JX; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Liu XC; Lab of Biorefinery, Shanghai Advanced Research Institute, Chinese Academy of Sciences, No. 99 Haike Road, Pudong, Shanghai, 201210, China.
  • Du GL; Lab of Biorefinery, Shanghai Advanced Research Institute, Chinese Academy of Sciences, No. 99 Haike Road, Pudong, Shanghai, 201210, China.
  • Sun JS; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Shi JP; Lab of Biorefinery, Shanghai Advanced Research Institute, Chinese Academy of Sciences, No. 99 Haike Road, Pudong, Shanghai, 201210, China.
  • Zhang BG; University of Chinese Academy of Sciences, Beijing, 100049, China.
Microb Cell Fact ; 20(1): 229, 2021 Dec 23.
Article em En | MEDLINE | ID: mdl-34949197
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fitosteróis / Esteroides / Pró-Fármacos / Redes e Vias Metabólicas / Mycobacteriaceae Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fitosteróis / Esteroides / Pró-Fármacos / Redes e Vias Metabólicas / Mycobacteriaceae Idioma: En Ano de publicação: 2021 Tipo de documento: Article