Mechanism of Elian granules in the treatment of precancerous lesions of gastric cancer in rats through the MAPK signalling pathway based on network pharmacology.

Yi, Zhirong; Jia, Qingling; Lin, Yili; Wang, Yujiao; Cong, Jun; Gu, Zhijian; Ling, Jianghong; Cai, Gan

Yi, Zhirong; Jia, Qingling; Lin, Yili; Wang, Yujiao; Cong, Jun; Gu, Zhijian; Ling, Jianghong; Cai, Gan.

Afiliação

Yi Z; The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, People's Republic of China.
Jia Q; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Lin Y; The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, People's Republic of China.
Wang Y; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Cong J; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Gu Z; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Ling J; The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, People's Republic of China.
Cai G; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

Pharm Biol ; 60(1): 87-95, 2022 Dec.

Article em En | MEDLINE | ID: mdl-34962453

Assuntos

Medicamentos de Ervas Chinesas/farmacologia; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Lesões Pré-Cancerosas/tratamento farmacológico; Neoplasias Gástricas/tratamento farmacológico; Animais; Modelos Animais de Doenças; Proteínas Quinases JNK Ativadas por Mitógeno/genética; Masculino; Metilnitronitrosoguanidina; Farmacologia em Rede; Ratos; Ratos Sprague-Dawley; Regulação para Cima/efeitos dos fármacos; Proteínas Quinases p38 Ativadas por Mitógeno/genética

Palavras-chave

Chinese medicine formula; bioinformation technology; biological network analysis; digestive disease; molecular mechanism

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lesões Pré-Cancerosas / Neoplasias Gástricas / Medicamentos de Ervas Chinesas / Sistema de Sinalização das MAP Quinases Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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