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Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS.
Hilpert, Kai; Gani, Jurnorain; Rumancev, Christoph; Simpson, Nathan; Lopez-Perez, Paula Matilde; Garamus, Vasil M; von Gundlach, Andreas Robert; Markov, Petar; Scocchi, Marco; Mikut, Ralf; Rosenhahn, Axel.
Afiliação
  • Hilpert K; Institute of Infection and Immunology, St. George's, University of London, London, United Kingdom.
  • Gani J; Institute of Infection and Immunology, St. George's, University of London, London, United Kingdom.
  • Rumancev C; Laboratory Analytical Chemistry - Biointerfaces, Ruhr University Bochum, Bochum, Germany.
  • Simpson N; Institute of Infection and Immunology, St. George's, University of London, London, United Kingdom.
  • Lopez-Perez PM; TiKa Diagnostics Ltd, London, United Kingdom.
  • Garamus VM; Helmholtz-Zentrum Hereon, Geesthacht, Germany.
  • von Gundlach AR; Laboratory Analytical Chemistry - Biointerfaces, Ruhr University Bochum, Bochum, Germany.
  • Markov P; European Molecular Biology Laboratory, Hamburg Outstation, Hamburg, Germany.
  • Scocchi M; Department of Life Sciences, University of Trieste, Trieste, Italy.
  • Mikut R; Institute for Automation and Applied Informatics (IAI), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
  • Rosenhahn A; Laboratory Analytical Chemistry - Biointerfaces, Ruhr University Bochum, Bochum, Germany.
Front Pharmacol ; 12: 769739, 2021.
Article em En | MEDLINE | ID: mdl-34966279

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article