Virulence of Herpes Simplex Virus 1 Harboring a UAG Stop Codon between the First and Second Initiation Codon in the Thymidine Kinase Gene.

Nguyen, Phu Hoang Anh; Yamada, Souichi; Harada, Shizuko; Fukushi, Shuetsu; Mizuguchi, Masashi; Saijo, Masayuki

Nguyen, Phu Hoang Anh; Yamada, Souichi; Harada, Shizuko; Fukushi, Shuetsu; Mizuguchi, Masashi; Saijo, Masayuki.

Afiliação

Nguyen PHA; Department of Virology 1, National Institute of Infectious Diseases, Japan.
Yamada S; Department of Developmental Medical Sciences, The University of Tokyo, Japan.
Harada S; Department of Virology 1, National Institute of Infectious Diseases, Japan.
Fukushi S; Department of Virology 1, National Institute of Infectious Diseases, Japan.
Mizuguchi M; Department of Virology 1, National Institute of Infectious Diseases, Japan.
Saijo M; Department of Developmental Medical Sciences, The University of Tokyo, Japan.

Jpn J Infect Dis ; 75(4): 368-373, 2022 Jul 22.

Article em En | MEDLINE | ID: mdl-34980708

Assuntos

Códon de Iniciação; Códon de Terminação; Herpesvirus Humano 1; Timidina Quinase; Aciclovir; Animais; Antivirais/farmacologia; Códon de Iniciação/genética; Códon de Terminação/genética; Herpesvirus Humano 1/genética; Herpesvirus Humano 1/patogenicidade; Camundongos; Mutação; Timidina Quinase/genética; Virulência/genética

Palavras-chave

acyclovir resistance; amber mutation; herpes simplex virus 1; viral thymidine kinase; virulence

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timidina Quinase / Herpesvirus Humano 1 / Códon de Terminação / Códon de Iniciação Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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