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Altered action potential waveform and shorter axonal initial segment in hiPSC-derived motor neurons with mutations in VRK1.
Bos, Rémi; Rihan, Khalil; Quintana, Patrice; El-Bazzal, Lara; Bernard-Marissal, Nathalie; Da Silva, Nathalie; Jabbour, Rosette; Mégarbané, André; Bartoli, Marc; Brocard, Frédéric; Delague, Valérie.
Afiliação
  • Bos R; Aix Marseille Univ, CNRS, Institut de Neurosciences de la Timone (INT), UMR 7289, Marseille, France. Electronic address: remi.bos@univ-amu.fr.
  • Rihan K; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.
  • Quintana P; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.
  • El-Bazzal L; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.
  • Bernard-Marissal N; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.
  • Da Silva N; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.
  • Jabbour R; Neurology Division, Department of Internal Medicine, St George Hospital University Medical Center, University of Balamand, Beirut, Lebanon.
  • Mégarbané A; Department of Human Genetics, Gilbert and RoseMary Chagoury Hospital, Lebanese American University, Byblos, Lebanon.
  • Bartoli M; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.
  • Brocard F; Aix Marseille Univ, CNRS, Institut de Neurosciences de la Timone (INT), UMR 7289, Marseille, France.
  • Delague V; Aix Marseille Univ, Inserm, MMG, U 1251, Institut Marseille Maladies Rares (MarMaRa), Marseille, France. Electronic address: valerie.delague@univ-amu.fr.
Neurobiol Dis ; 164: 105609, 2022 03.
Article em En | MEDLINE | ID: mdl-34990802
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Potenciais de Ação / Proteínas Serina-Treonina Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Segmento Inicial do Axônio / Neurônios Motores Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Potenciais de Ação / Proteínas Serina-Treonina Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Segmento Inicial do Axônio / Neurônios Motores Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article