These organoids have some nerve: Uniting three germ layers in a human gastric model system.

Koppes, Abigail N; Koppes, Ryan A; Nichols, Kyla N

Koppes, Abigail N; Koppes, Ryan A; Nichols, Kyla N.

Afiliação

Koppes AN; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, Boston, MA 02115, USA; Department of Biology, Northeastern University, Boston, MA 02115, USA. Electronic address: a.koppes@northeastern.edu.
Koppes RA; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.
Nichols KN; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Cell Stem Cell ; 29(1): 5-6, 2022 01 06.

Article em En | MEDLINE | ID: mdl-34995495

ABSTRACT

ABSTRACT

Gastrointestinal organoids provide an accessible model for studying human development and disease. In this issue of Cell Stem Cell, Eicher et al. (2022) direct human pluripotent stem cells to incorporate three germ layers into gastric organoids, recapitulating the structure and function of human gut tissue in an in vitro model.

Assuntos

Organoides; Células-Tronco Pluripotentes; Camadas Germinativas; Humanos; Modelos Biológicos; Estômago

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Células-Tronco Pluripotentes Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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