Bimetallic Fe-Cu Nanocomposites on Sand Particles for the Inactivation of Clinical Isolates and Point-of-Use Water Filtration.
ACS Appl Bio Mater
; 1(6): 2153-2166, 2018 Dec 17.
Article
em En
| MEDLINE
| ID: mdl-34996276
ABSTRACT
Bimetallic Fe-Cu nanocomposites with an average size of 26.4 ± 4.7 nm were prepared on the surface of fine sand particles by modified coprecipitation and the chemical reduction method and were applied as an in vitro broad spectrum antimicrobial agent and recyclable hand-held water filter to sieve bacteria and metals. The size of the nanocomposites could be further reduced to 11.8 ± 1.6 nm when prepared after ball milling the sand particles, keeping the antimicrobial property intact. The results showed that the chemical nature and morphology of the nanocomposites had a great effect on both Gram-positive and Gram-negative bacteria with a minimum inhibitory concentration of 10.6 µg/mL and 13.8 µg/mL of copper, whereas the minimum bactericidal concentration was found to be 15.9 µg/mL and 21.2 µg/mL. The nanocomposites exhibited antimicrobial activity against multidrug-resistant bacteria as well as fungus isolated from different human biological samples like blood, urine, pus, and wound swabs. The nanocomposites were also capable of filtering a wide range bacteria like Acinetobacter baumannii, Escherichia coli, Salmonella typhi, Bacteroides fragilis, Salmonella paratyphi, Shigella dysenteriae, and Enterococcus faecalis, which are predominantly responsible for waterborne diseases. Further, the nanocomposites were used for the removal of hazardous metals like nickel, zinc, and lead. Leaching of copper and iron from the nanocomposites was within the permissible limit as per Bureau of Indian Standards (BIS) for Drinking Water (IS-10500-2012, second revision) as well as the International Standards for Drinking Water.
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MEDLINE
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Ano de publicação:
2018
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Article