Long non-coding RNA MALAT1 affects intermittent hypoxia-induced endothelial injury by regulating miR-142-3p/HMGB1.

Chen, Meng-Xue; Chen, Li-Da; Huang, Jian-Chai; Zeng, Ai-Ming; Huang, Jie-Feng; Lin, Qi-Chang

Chen, Meng-Xue; Chen, Li-Da; Huang, Jian-Chai; Zeng, Ai-Ming; Huang, Jie-Feng; Lin, Qi-Chang.

Afiliação

Chen MX; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong road, Taijiang district, Fuzhou, Fujian Province, 350005, People's Republic of China.
Chen LD; Department of Respiratory and Critical Care Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian Province, People's Republic of China.
Huang JC; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong road, Taijiang district, Fuzhou, Fujian Province, 350005, People's Republic of China.
Zeng AM; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong road, Taijiang district, Fuzhou, Fujian Province, 350005, People's Republic of China.
Huang JF; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong road, Taijiang district, Fuzhou, Fujian Province, 350005, People's Republic of China.
Lin QC; Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University, No 20, Chazhong road, Taijiang district, Fuzhou, Fujian Province, 350005, People's Republic of China. chang4e@126.com.

Sleep Breath ; 26(4): 2015-2024, 2022 12.

Article em En | MEDLINE | ID: mdl-35006556

Assuntos

Proteína HMGB1; MicroRNAs; RNA Longo não Codificante; Apneia Obstrutiva do Sono; Humanos; RNA Longo não Codificante/genética; RNA Longo não Codificante/metabolismo; Proteína HMGB1/genética; Proteína HMGB1/metabolismo; Proteína HMGB1/farmacologia; MicroRNAs/genética; Apoptose/genética; Células Endoteliais da Veia Umbilical Humana/metabolismo; Hipóxia/metabolismo; Apneia Obstrutiva do Sono/genética; Apneia Obstrutiva do Sono/metabolismo

Palavras-chave

Apoptosis; Endothelial injury; Intermittent hypoxia; MALAT1; MiR-142-3p; Obstructive sleep apnea

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apneia Obstrutiva do Sono / Proteína HMGB1 / MicroRNAs / RNA Longo não Codificante Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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