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'Rapid speed of response to ECT in bipolar depression: A chart review.
Scheepstra, K W F; van Doorn, J B; Scheepens, D S; de Haan, A; Schukking, N; Zantvoord, J B; Lok, A.
Afiliação
  • Scheepstra KWF; Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105, BA, Amsterdam, the Netherlands. Electronic address: k.w.scheepstra@amst
  • van Doorn JB; Department of Psychological Methods, University of Amsterdam, Valckeniersstraat 59, 1018, XA, Amsterdam, the Netherlands.
  • Scheepens DS; Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands.
  • de Haan A; Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands.
  • Schukking N; Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands.
  • Zantvoord JB; Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands.
  • Lok A; Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105, AZ, Amsterdam, the Netherlands.
J Psychiatr Res ; 147: 34-38, 2022 03.
Article em En | MEDLINE | ID: mdl-35007809
ABSTRACT

OBJECTIVE:

To validate a faster speed of response to electroconvulsive therapy (ECT) for bipolar depression (BPD) compared to major depressive disorder (MDD)

METHOD:

Retrospective chart review on an ECT cohort in an academic hospital setting. Speed of response was defined by the number of ECT treatments needed for response or remission.

RESULTS:

Sixty-four depressed patients were included, of whom 53 (MDD 40, BPD 13) could be analyzed. The bipolar group responded faster with a mean difference of 3.3 fewer ECT treatments to meet response criteria (MDD 10.4 vs. BPD 7.1, p = 0.054). When using mixed effects regression models for the response/remitter group (n = 35), a faster response for the bipolar group (AIC 252.83 vs 258.55, χ2 = 11.72, p = 0.008) was shown. Other factors, such as psychotic features or comorbidity, did not influence the speed of response.

CONCLUSION:

This chart review of an ECT cohort in an naturalistic academic hospital setting shows an evident and clinically relevant faster speed of response in bipolar depression.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Transtorno Depressivo Maior / Eletroconvulsoterapia Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Transtorno Depressivo Maior / Eletroconvulsoterapia Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article