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Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents.
Islam, Farhana; Doshi, Arpit; Robles, Andrew J; Quadery, Tasdique M; Zhang, Xin; Zhou, Xilin; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem.
Afiliação
  • Islam F; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
  • Doshi A; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
  • Robles AJ; Department of Pharmacology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
  • Quadery TM; Mays Cancer Center, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
  • Zhang X; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
  • Zhou X; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
  • Hamel E; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA.
  • Mooberry SL; Molecular Pharmacology Branch, Developmental Therapeutics Program, Frederick National Laboratory for Cancer Research, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
  • Gangjee A; Department of Pharmacology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Molecules ; 27(1)2022 Jan 05.
Article em En | MEDLINE | ID: mdl-35011550
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Desenho de Fármacos / Moduladores de Tubulina / Técnicas de Química Sintética Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Desenho de Fármacos / Moduladores de Tubulina / Técnicas de Química Sintética Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article