Synthesis of Chromeno[2,3-d]pyrimidin-5-one Derivatives from 1,3,5-Triazinanes via Two Different Reaction Pathways.
J Org Chem
; 87(2): 1348-1356, 2022 01 21.
Article
em En
| MEDLINE
| ID: mdl-35012316
ABSTRACT
1,3,5-Triazinanes, as a kind of versatile building block, are applied in the synthesis of chromeno[2,3-d]pyrimidin-5-one derivatives via two different reaction modes, which perfectly exhibits the powerful function of 1,3,5-triazinane as a three-atom synthon along with the structure variation of another substrate. The two annulation reactions proceed under mild conditions and bear broad substrate scope and high yield.
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2022
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Article