Integrative omics analysis identifies biomarkers of idiopathic pulmonary fibrosis.

Zheng, Peiyan; Sun, Shixue; Wang, Jingxian; Cheng, Zhangkai Jason; Lei, Kuan Cheok; Xue, Mingshan; Zhang, Teng; Huang, Huimin; Zhang, Xiaohua Douglas; Sun, Baoqing

Zheng, Peiyan; Sun, Shixue; Wang, Jingxian; Cheng, Zhangkai Jason; Lei, Kuan Cheok; Xue, Mingshan; Zhang, Teng; Huang, Huimin; Zhang, Xiaohua Douglas; Sun, Baoqing.

Afiliação

Zheng P; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Sun S; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Wang J; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Cheng ZJ; National Joint Local Engineering Laboratory for Cell Engineering and Biomedicine Technique, Guizhou Province Key Laboratory of Regenerative Medicine, Key Laboratory of Adult Stem Cell Translational Research (Chinese Academy of Medical Sciences), Guizhou Medical University, Guizhou, 550025, China.
Lei KC; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Xue M; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Zhang T; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Huang H; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Zhang XD; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Sun B; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China. douglaszhang@um.edu.mo.

Cell Mol Life Sci ; 79(1): 66, 2022 Jan 11.

Article em En | MEDLINE | ID: mdl-35015148

Assuntos

Butirofilinas/genética; Matriz Extracelular/metabolismo; Fibrose Pulmonar Idiopática/genética; Fibrose Pulmonar Idiopática/patologia; Proteínas Proteolipídicas Associadas a Linfócitos e Mielina/genética; Animais; Biomarcadores/análise; Bleomicina/toxicidade; Diferenciação Celular/genética; Proliferação de Células/genética; Modelos Animais de Doenças; Feminino; Perfilação da Expressão Gênica; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Pessoa de Meia-Idade; Proteoma/genética; Proteômica; RNA-Seq; Transcriptoma/genética; Cicatrização/genética

Palavras-chave

AEC injury; Immune responses; Multi-omics analysis; Myofibroblast proliferation; Whole-genome expression

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Matriz Extracelular / Fibrose Pulmonar Idiopática / Proteínas Proteolipídicas Associadas a Linfócitos e Mielina / Butirofilinas Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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