Sonographic pulmonary response after tracheal occlusion in fetuses with severe isolated congenital diaphragmatic hernia.
J Clin Ultrasound
; 50(2): 185-190, 2022 Feb.
Article
em En
| MEDLINE
| ID: mdl-35019149
ABSTRACT
PURPOSE:
To report the longitudinal lung growth and prognosis of fetuses with severe left sided congenital diaphragmatic hernia (CDH) treated with fetoscopic tracheal occlusion (FETO) in a single institution.METHODS:
Fetal lung size (observed-to-expected lung area to head circumference [o/e-LHR]) was measured in seven consecutive fetuses with isolated severe left-sided CDH who underwent FETO. Fetal lung growth was used to prognosticate survival and need for ECMO.RESULTS:
Seven consecutive fetuses had a FETO procedure in the timeframe of this study. A total of 44 longitudinal ultrasound were performed to evaluate lung development. FETO was performed at GA 28.5 ± 0.5 weeks. Five (71.4%) infants survived to one-year follow-up and ECMO was needed in three patients (42.8%). Fetal lung response was observed in all fetuses; mean o/e-LHR increased from 22.5% ± 1.4 before FETO to 44.4% ± 9.8 before delivery. Infants who survived had a higher percentage of fetal lung growth (21.8%) than those who died (8.25%).CONCLUSION:
Our study supports the hypothesis that FETO promotes fetal lung growth in fetuses with severe left-sided CDH, and the fetal pulmonary response seems to be associated with improved outcomes after the procedure.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Hérnias Diafragmáticas Congênitas
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
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Infant
/
Pregnancy
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article