DNase 1 Protects From Increased Thrombin Generation and Venous Thrombosis During Aging: Cross-Sectional Study in Mice and Humans.

Kumar, Rahul; Sonkar, Vijay K; Swamy, Jagadish; Ahmed, Azaj; Sharathkumar, Anjali A; Pierce, Gary L; Dayal, Sanjana

Kumar, Rahul; Sonkar, Vijay K; Swamy, Jagadish; Ahmed, Azaj; Sharathkumar, Anjali A; Pierce, Gary L; Dayal, Sanjana.

Afiliação

Kumar R; Department of Internal Medicine University of Iowa Iowa City IA.
Sonkar VK; Department of Internal Medicine University of Iowa Iowa City IA.
Swamy J; Department of Internal Medicine University of Iowa Iowa City IA.
Ahmed A; Department of Internal Medicine University of Iowa Iowa City IA.
Sharathkumar AA; Department of Pediatrics University of Iowa Iowa City IA.
Pierce GL; Department of Health and Human Physiology College of Liberal Arts and Sciences University of Iowa Iowa City IA.
Dayal S; Department of Internal Medicine University of Iowa Iowa City IA.

J Am Heart Assoc ; 11(2): e021188, 2022 01 18.

Article em En | MEDLINE | ID: mdl-35023342

Assuntos

Ácidos Nucleicos Livres; Trombose; Trombose Venosa; Idoso; Envelhecimento; Animais; Estudos Transversais; Desoxirribonucleases; Glutationa Peroxidase; Histonas; Humanos; Camundongos; Pessoa de Meia-Idade; Neutrófilos/metabolismo; Trombina/metabolismo; Trombose Venosa/genética; Trombose Venosa/prevenção & controle

Palavras-chave

age; aging; extracellular traps; oxidative stress; thrombosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Trombose Venosa / Ácidos Nucleicos Livres Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Aged / Animals / Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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