Association of the MAOA-uVNTR polymorphism with psychopathic traits may change from childhood to adolescence.
Eur Arch Psychiatry Clin Neurosci
; 272(8): 1517-1521, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35038001
ABSTRACT
Psychopathic traits can lead to violence, making it a serious public health concern. Genetic factors contribute to the aetiology of psychopathy. We examined whether monoamine oxidase A (MAOA-uVNTR) was associated with psychopathic traits measured quantitatively from controls through clinically aggressive youth (n = 336). Subjects were sub-categorized into at or above, and below age 13 years. Results reveal that males below age 13 were more likely to display psychopathic traits with the MAOA long variant, whereas males above age 13 years were more likely to display with the short variant. This suggests that developmental factors may be crucial for understanding the role of the MAOA polymorphism in psychopathic traits in males.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Repetições Minissatélites
/
Monoaminoxidase
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article