Biopsy-based optimization and calibration of a signal-intensity-ratio-based MRI method (1.5 Tesla) in a dextran-iron loaded mini-pig model, enabling estimation of very high liver iron concentrations.

Jensen, Peter D; Nielsen, Asbjørn H; Simonsen, Carsten W; Jensen, Kenneth K; Bøgsted, Martin; Jensen, Anne B H; Kjaergaard, Benedict

Jensen, Peter D; Nielsen, Asbjørn H; Simonsen, Carsten W; Jensen, Kenneth K; Bøgsted, Martin; Jensen, Anne B H; Kjaergaard, Benedict.

Afiliação

Jensen PD; Department of Hematology, University Hospital, Aalborg, Denmark. d222615@dadlnet.dk.
Nielsen AH; Department of the Built Environment, Aalborg University, Aalborg, Denmark.
Simonsen CW; Department of Radiology, Imaging Research Unit, Aalborg University Hospital, Aalborg, Denmark.
Jensen KK; Department of Radiology, Imaging Research Unit, Aalborg University Hospital, Aalborg, Denmark.
Bøgsted M; Department of Hematology, University Hospital, Aalborg, Denmark.
Jensen ABH; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Kjaergaard B; The Faculty of Medicine, Aalborg University, Aalborg, Denmark.

MAGMA ; 35(5): 843-859, 2022 Oct.

Article em En | MEDLINE | ID: mdl-35038062

Assuntos

Dextranos; Sobrecarga de Ferro; Animais; Biópsia; Calibragem; Ferro; Sobrecarga de Ferro/diagnóstico por imagem; Fígado/diagnóstico por imagem; Fígado/patologia; Imageamento por Ressonância Magnética/métodos; Suínos; Porco Miniatura

Palavras-chave

Experimental animal models; Iron overload; Liver iron concentration; Magnetic resonance imaging; Quantitative imaging

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dextranos / Sobrecarga de Ferro Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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