Result Turnaround Time of RT-PCR for SARS-CoV-2 is the Main Cause of COVID-19 Diagnostic Delay: A Country-Wide Observational Study of Mexico and Colombia.
Rev Invest Clin
; 74(2): 071-080, 2022 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-35038256
ABSTRACT
BACKGROUND:
Delay in COVID-19 diagnosis due to late real-time reverse transcription-polymerase chain reaction reporting has been described to be an important cause of suboptimal COVID-19 surveillance and outbreak containment.OBJECTIVE:
The objective of the study was to determine the duration of diagnostic delay due to test turnaround time and its association with marginalization status.METHODS:
In this observational study using national open data of Mexico and Colombia, we quantified the delay in COVID-19 diagnosis that occurred in both countries. We considered two periods that contributed to the delay in diagnosis the time from symptom onset until testing (delay-one) and test turnaround time (delay-two). Marginalization status was determined according to country-specific scores.RESULTS:
Among 3,696,773 patients from Mexico and Colombia, delay-two was generally longer than delay-one. Median delay-one was 3 days and delay-two 7 days in Colombia, while in Mexico, they were 3 days and 4 days, respectively. In Colombia, worse marginalization status prolonged delaytwo. In Mexico, a lower number and percentage of rapid tests were performed in areas with worse marginalization.CONCLUSION:
Diagnostic delay was mostly due to test turnaround time. Marginalization status was an important barrier to diagnostic test access.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
SARS-CoV-2
/
COVID-19
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Humans
País como assunto:
America do sul
/
Colombia
/
Mexico
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article