High-throughput glycosylation analysis of intact monoclonal antibodies by mass spectrometry coupled with capillary electrophoresis and liquid chromatography.

Naumann, Lukas; Schlossbauer, Patrick; Klingler, Florian; Hesse, Friedemann; Otte, Kerstin; Neusüß, Christian

Naumann, Lukas; Schlossbauer, Patrick; Klingler, Florian; Hesse, Friedemann; Otte, Kerstin; Neusüß, Christian.

Afiliação

Naumann L; Department of Chemistry, Aalen University, Aalen, Germany.
Schlossbauer P; Department of applied Biotechnology, Biberach University of Applied Sciences, Biberach, Germany.
Klingler F; Department of applied Biotechnology, Biberach University of Applied Sciences, Biberach, Germany.
Hesse F; Department of applied Biotechnology, Biberach University of Applied Sciences, Biberach, Germany.
Otte K; Department of applied Biotechnology, Biberach University of Applied Sciences, Biberach, Germany.
Neusüß C; Department of Chemistry, Aalen University, Aalen, Germany.

J Sep Sci ; 45(12): 2034-2044, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35044720

Assuntos

Anticorpos Monoclonais; Eletroforese Capilar; Anticorpos Monoclonais/química; Cromatografia Líquida; Eletroforese Capilar/métodos; Glicosilação; Espectrometria de Massas/métodos

Palavras-chave

antibodies; glycosylation; high throughput screening; mass spectrometry

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eletroforese Capilar / Anticorpos Monoclonais Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eletroforese Capilar / Anticorpos Monoclonais Idioma: En Ano de publicação: 2022 Tipo de documento: Article