Cadmium exposure reprograms energy metabolism of hematopoietic stem cells to promote myelopoiesis at the expense of lymphopoiesis in mice.

Zhao, Yifan; He, Jinyi; Zhu, Tingting; Zhang, Yufan; Zhai, Yue; Xue, Peng; Yao, Ye; Zhou, Zhijun; He, Miao; Qu, Weidong; Zhang, Yubin

Zhao, Yifan; He, Jinyi; Zhu, Tingting; Zhang, Yufan; Zhai, Yue; Xue, Peng; Yao, Ye; Zhou, Zhijun; He, Miao; Qu, Weidong; Zhang, Yubin.

Afiliação

Zhao Y; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
He J; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Zhu T; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Zhang Y; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Zhai Y; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Xue P; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Yao Y; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Zhou Z; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
He M; State Key Laboratory of Medical Neurobiology, Institutes of Brain Sciences, Fudan University, Shanghai 200032, China.
Qu W; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China.
Zhang Y; School of Public Health and Key Laboratory of Public Health Safety, MOE, Fudan University, Shanghai 200032, China. Electronic address: yz001@fudan.edu.cn.

Ecotoxicol Environ Saf ; 231: 113208, 2022 Feb.

Article em En | MEDLINE | ID: mdl-35051759

Assuntos

Cádmio; Mielopoese; Animais; Cádmio/toxicidade; Células-Tronco Hematopoéticas; Linfopoese; Potencial da Membrana Mitocondrial; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

Cadmium; Energy metabolism; Glycolysis; Hematopoietic stem cells; Lymphopoiesis; Mitochondrial oxidative phosphorylation; Myelopoiesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cádmio / Mielopoese Tipo de estudo: Health_economic_evaluation Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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