Flavivirus recruits the valosin-containing protein-NPL4 complex to induce stress granule disassembly for efficient viral genome replication.

Arakawa, Masashi; Tabata, Keisuke; Ishida, Kotaro; Kobayashi, Makiko; Arai, Arisa; Ishikawa, Tomohiro; Suzuki, Ryosuke; Takeuchi, Hiroaki; Tripathi, Lokesh P; Mizuguchi, Kenji; Morita, Eiji

Arakawa, Masashi; Tabata, Keisuke; Ishida, Kotaro; Kobayashi, Makiko; Arai, Arisa; Ishikawa, Tomohiro; Suzuki, Ryosuke; Takeuchi, Hiroaki; Tripathi, Lokesh P; Mizuguchi, Kenji; Morita, Eiji.

Afiliação

Arakawa M; Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan; Division of Biomolecular Function, Bioresources Science, United Graduate School of Agricultural Sciences, Iwate University, Morioka, Japan.
Tabata K; Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan; Department of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan; Laboratory of Viral Infection, Research Institute for Microbial Diseases, Osaka University, Osa
Ishida K; Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan; Division of Biomolecular Function, Bioresources Science, United Graduate School of Agricultural Sciences, Iwate University, Morioka, Japan.
Kobayashi M; Laboratory of Viral Infection, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Arai A; Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan.
Ishikawa T; Department of Microbiology, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Suzuki R; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.
Takeuchi H; Department of Molecular Virology, Tokyo Medical and Dental University, Tokyo, Japan.
Tripathi LP; Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Mizuguchi K; Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan; Institute for Protein Research, Osaka University, Osaka, Japan.
Morita E; Department of Biochemistry and Molecular Biology, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan; Division of Biomolecular Function, Bioresources Science, United Graduate School of Agricultural Sciences, Iwate University, Morioka, Japan; Laboratory of Viral Infection,

J Biol Chem ; 298(3): 101597, 2022 03.

Article em En | MEDLINE | ID: mdl-35063505

Assuntos

Vírus da Encefalite Japonesa (Espécie); Flavivirus; Proteínas Nucleares; Grânulos de Estresse; Proteína com Valosina; Proteínas não Estruturais Virais; Replicação Viral; Vírus da Encefalite Japonesa (Espécie)/genética; Vírus da Encefalite Japonesa (Espécie)/metabolismo; Vírus da Encefalite Japonesa (Espécie)/fisiologia; Flavivirus/genética; Flavivirus/metabolismo; Flavivirus/fisiologia; Genoma Viral; Humanos; Proteínas Nucleares/metabolismo; RNA Viral/genética; Grânulos de Estresse/genética; Grânulos de Estresse/metabolismo; Proteína com Valosina/metabolismo; Proteínas não Estruturais Virais/genética; Proteínas não Estruturais Virais/metabolismo; Replicação Viral/fisiologia

Palavras-chave

NPL4; NS4B; VCP/p97; flavivirus replication; stress granules

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Proteínas Nucleares / Proteínas não Estruturais Virais / Vírus da Encefalite Japonesa (Espécie) / Flavivirus / Proteína com Valosina / Grânulos de Estresse Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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