Spatial visualization of drug uptake and distribution in Fasciola hepatica using high-resolution AP-SMALDI mass spectrometry imaging.

Morawietz, Carolin M; Peter Ventura, Alejandra M; Grevelding, Christoph G; Haeberlein, Simone; Spengler, Bernhard

Morawietz, Carolin M; Peter Ventura, Alejandra M; Grevelding, Christoph G; Haeberlein, Simone; Spengler, Bernhard.

Afiliação

Morawietz CM; Institute of Inorganic and Analytical Chemistry, Justus Liebig University Giessen, Giessen, Germany.
Peter Ventura AM; Institute of Inorganic and Analytical Chemistry, Justus Liebig University Giessen, Giessen, Germany.
Grevelding CG; Institute of Parasitology, Biomedical Research Center Seltersberg (BFS), Justus Liebig University Giessen, Giessen, Germany.
Haeberlein S; Institute of Parasitology, Biomedical Research Center Seltersberg (BFS), Justus Liebig University Giessen, Giessen, Germany.
Spengler B; Institute of Inorganic and Analytical Chemistry, Justus Liebig University Giessen, Giessen, Germany. bernhard.spengler@anorg.chemie.uni-giessen.de.

Parasitol Res ; 121(4): 1145-1153, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35067744

Assuntos

Anti-Helmínticos; Fasciola hepatica; Fasciolíase; Navegação Espacial; Animais; Anti-Helmínticos/uso terapêutico; Benzimidazóis; Fasciola hepatica/metabolismo; Fasciolíase/tratamento farmacológico; Fasciolíase/parasitologia; Espectrometria de Massas

Palavras-chave

Drugs; Fasciola hepatica; Mass spectrometry imaging; Triclabendazole; Triclabendazole sulfoxide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fasciola hepatica / Fasciolíase / Navegação Espacial / Anti-Helmínticos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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