Diarylamine Synthesis via Desulfinylative Smiles Rearrangement.
Org Lett
; 24(5): 1132-1135, 2022 02 11.
Article
em En
| MEDLINE
| ID: mdl-35094513
ABSTRACT
Diarylamines are obtained directly from sulfinamides through a novel rearrangement sequence. The transformation is transition metal-free and proceeds under mild conditions, providing facile access to highly sterically hindered diarylamines that are otherwise inaccessible by traditional SNAr chemistry. The reaction highlights the distinct reactivity of the sulfinamide group in Smiles rearrangements versus that of the more common sulfonamides.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article