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Overcoming acquired resistance to third-generation EGFR inhibitors by targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition, Bax activation, or both.
Ma, Guangzhi; Deng, Yunfu; Qian, Luxi; Vallega, Karin A; Zhang, Guojing; Deng, Xingming; Owonikoko, Taofeek K; Ramalingam, Suresh S; Fang, Douglas D; Zhai, Yifan; Sun, Shi-Yong.
Afiliação
  • Ma G; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Deng Y; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
  • Qian L; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
  • Vallega KA; Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Zhang G; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
  • Deng X; Department of Radiation Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research and The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Owonikoko TK; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
  • Ramalingam SS; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
  • Fang DD; Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
  • Zhai Y; Department of Medicine, University of Pittsburgh and Hillman Cancer Center, Pittsburgh, PA, USA.
  • Sun SY; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
Oncogene ; 41(12): 1691-1700, 2022 03.
Article em En | MEDLINE | ID: mdl-35102249
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article