The value of preoperative lymphocytes-to-monocytes ratio in predicting lymph node metastasis in gastric cancer.
Transl Cancer Res
; 8(5): 2053-2058, 2019 Sep.
Article
em En
| MEDLINE
| ID: mdl-35116954
ABSTRACT
BACKGROUND:
This study was aimed to evaluate value of preoperative lymphocytes-to-monocytes ratio (LMR) as a predictor for lymph node metastasis in gastric cancer.METHODS:
Patients with pathologically diagnosed malignant gastric tumor were reviewed retrospectively. Patients' demographic data, clinical manifestations and LMR were collected. The postoperative pathology data including the tumor size, tumor sites, differentiation degree of tumor, depth of tumor invasion, metastatic lymph nodes, total dissected lymph nodes, distant metastasis, vessel carcinoma embolus, neural invasion, Lauren's classification, Ki-67 and TNM stage were collected. Receiver operating characteristic curve (ROC) was used to determine the cut-off point of LMR. The association between LMR and the clinicopathologic factors was further analyzed.RESULTS:
A total of 177 subjects were enrolled into the study. LMR =3.79 was used as cut-off point; the patients with LMR ≥3.79 were classified as high-LMR group (123 cases) and the patients with LMR <3.79 as low-LMR group (54 cases). LMR was an independent risk factor for lymph node metastasis.CONCLUSIONS:
Low preoperative LMR was positively correlated with lymph node metastasis in gastric cancer patients, and had predictive value for lymph node metastasis in gastric cancer patients.
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article