Do clinical outcomes differ for day-5 versus day-6 single embryo transfers controlled for endometrial factor?
Reprod Biomed Online
; 44(3): 478-485, 2022 Mar.
Article
em En
| MEDLINE
| ID: mdl-35125295
ABSTRACT
RESEARCH QUESTION Is there is a difference in clinical outcomes between day-5 versus day-6 blastocysts when transferred in a personalized embryo transfer (PET) cycle guided by Endometrial Receptivity Analysis (ERA)? DESIGN:
Multicentre, retrospective study; 260 patients who underwent a single embryo transfer with either a day-5 or day-6 blastocyst in a PET cycle guided by ERA between January 2017 and December 2019.RESULTS:
A total of 260 blastocysts were transferred in a single embryo PET cycle guided by ERA. Of those, 183 (70.4%) were day-5 blastocysts and 77 (29.6%) were day-6 blastocysts. Clinical outcomes were similar when transferring day-5 blastocysts versus day-6 blastocysts pregnancy rate was 75.4% (138/183) and 70.1% (54/77) (Pâ¯=â¯0.465); implantation rate was 67.8% (124/183) and 63.6% (49/77) (Pâ¯=â¯0.476); and ongoing pregnancy rate was 57.9% (106/183) and 58.4% (45/77) (Pâ¯=â¯0.728), respectively.CONCLUSIONS:
The data suggest that the clinical potential of day-5 and day-6 blastocysts are similar, as no difference in clinical outcomes are observed when transferring at the time of optimal endometrial receptivity as determined by ERA.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Criopreservação
/
Transferência de Embrião Único
Tipo de estudo:
Observational_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article