Hyperhomocysteinemia and cardiovascular diseases.
Ann Biol Clin (Paris)
; 80(1): 7-14, 2022 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-35129442
ABSTRACT
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, which is not acquired through the diet, but rather synthesized as an intermediate metabolite in the methionine cycle. Hcy is present in plasma, with normal levels between 5 and 15 µmol/L, a slightly elevated level between 15 to 30 µmol/L, moderate from 30 to 100 µmol/L and a value > 100 µmol/L classified as severe hyperhomocysteinemia (HHcy). HHcy has been associated with inflammation and atherosclerosis and is considered an independent risk factor for cardiovascular diseases (CVD). Here, we review the main evidence showing the association and the possible involvement of HHcy in the most common CVD.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
/
Hiper-Homocisteinemia
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article