The cyanotoxin cylindrospermopsin slows down cell cycle progression and extends metaphase duration in immortalised human airway epithelial cells.

Vennmann, Janita; Edelmann, Julia; Gudra, Celine; Ziesemer, Sabine; Hildebrandt, Jan-Peter

Vennmann, Janita; Edelmann, Julia; Gudra, Celine; Ziesemer, Sabine; Hildebrandt, Jan-Peter.

Afiliação

Vennmann J; Animal Physiology and Biochemistry, University of Greifswald, Felix Hausdorff-Strasse 1, D - 17489, Greifswald, Germany. Electronic address: janita.vennmann@web.de.
Edelmann J; Animal Physiology and Biochemistry, University of Greifswald, Felix Hausdorff-Strasse 1, D - 17489, Greifswald, Germany. Electronic address: julia.edelmann@stud.uni-greifswald.de.
Gudra C; Animal Physiology and Biochemistry, University of Greifswald, Felix Hausdorff-Strasse 1, D - 17489, Greifswald, Germany. Electronic address: line-jena@web.de.
Ziesemer S; Animal Physiology and Biochemistry, University of Greifswald, Felix Hausdorff-Strasse 1, D - 17489, Greifswald, Germany. Electronic address: sabine.ziesemer@uni-greifswald.de.
Hildebrandt JP; Animal Physiology and Biochemistry, University of Greifswald, Felix Hausdorff-Strasse 1, D - 17489, Greifswald, Germany. Electronic address: jph@uni-greifswald.de.

Toxicon ; 209: 28-35, 2022 Apr 15.

Article em En | MEDLINE | ID: mdl-35131292

Assuntos

Alcaloides; Toxinas de Cianobactérias; Alcaloides/toxicidade; Animais; Ciclo Celular; Divisão Celular; Toxinas de Cianobactérias/toxicidade; Células Epiteliais; Humanos; Metáfase

Palavras-chave

Airway epithelial cells; Cell attachment; Cell cycle; Cell proliferation; Cell spreading; Cyanotoxin; Cyclin B1; Cyclin D1; Cylindrospermopsin; Metaphase duration; Mitotic cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alcaloides / Toxinas de Cianobactérias Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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