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The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1ß/p38 MAPK pathway.
Su, Xue-Ling; Wang, Shu-Hui; Komal, Sumra; Cui, Liu-Gen; Ni, Rui-Cong; Zhang, Li-Rong; Han, Sheng-Na.
Afiliação
  • Su XL; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Wang SH; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Komal S; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Cui LG; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Ni RC; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China.
  • Zhang LR; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China. zhanglirongzzu@126.com.
  • Han SN; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China. hanshengna@126.com.
Acta Pharmacol Sin ; 43(9): 2289-2301, 2022 Sep.
Article em En | MEDLINE | ID: mdl-35132192
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conexina 43 / Caspase 1 / Infarto do Miocárdio Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conexina 43 / Caspase 1 / Infarto do Miocárdio Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article