Dysregulated kappa-opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence.

Wei, Gengze; Sirohi, Sunil; Walker, Brendan M

Wei, Gengze; Sirohi, Sunil; Walker, Brendan M.

Afiliação

Wei G; Laboratory of Alcoholism and Addictions Neuroscience, Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Sirohi S; Laboratory of Endocrine and Neuropsychiatric Disorders, Division of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans, Louisiana, USA.
Walker BM; Laboratory of Alcoholism and Addictions Neuroscience, Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.

Addict Biol ; 27(2): e13138, 2022 03.

Article em En | MEDLINE | ID: mdl-35138672

Assuntos

Alcoolismo; Receptores Opioides kappa; Alcoolismo/complicações; Alcoolismo/tratamento farmacológico; Animais; Masculino; Transtornos da Memória; Memória de Curto Prazo; Córtex Pré-Frontal/metabolismo; Ratos; Ratos Wistar

Palavras-chave

alcohol dependence; intermittent ethanol vapor; kappa opioid receptor; medial prefrontal cortex; withdrawal; working memory

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Opioides kappa / Alcoolismo Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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